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cleverMachine

cleverMachine

The clever machine is an algorithm to discriminate between two protein datasets using physico-chemical properties contained in their primary structures. The first dataset to submit contains a hypothetical signal (e.g., substrates of a particular chaperone) while the second represents the reference set (e.g., a cell lysate). This distinction is purely internal and only affects presentation of the results (there is no bias in the algorithm operation). Once the datasets are discriminated with a certain accuracy, a classifier is made available at service.tartaglialab.com/clever_classifier.



 

Submission reference: 966988


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Run mode
Normal run is recommended for majority of users and provides simplicity and robustness. Switching to expert mode enables multitude of additional features aimed at advanced users but at potential cost of increased computational time. Read more what could be done.

Normal run
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Upload a Positive dataset (FASTA format, at least 10 and at most 104 sequences)


Upload a Reference dataset (FASTA format, at least 10 and at most 104 sequences)




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Sample data

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mRNA binding proteins - The human RNA-binding proteins
[Castello, A. et al. (2012) Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins. Cell, 149, 1393–1406]