cleverClassifier

Analysis output

Information about the dataset:
Dataset title: baltz VS mRNA
Dataset filename: balz_pos_unique_latest.fasta
Reference dataset: link
Generated: 2013-12-17 18:16:53.645308
Classifier used: ExtraTR

Classification
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73.0% of your submitted dataset was classified as positive (P).

The strength is the test set fraction that can be assigned.
Redundancy analysis did not find significant overlap with training data.

Test set signal enrichment (vs. random data): 0.44

Scale combinations
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Reference dataset result (Positive vs. Negative)

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1
2
3
4
5
0.0
Positive set
Negative set
1.0
1
Number of combined properties
Combined coverage

X vs. Negative

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1
2
3
4
5
0.0
Positive set
Negative set
1.0
1
Number of combined properties
Combined coverage

Combination statistics
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HINT: Click the table rows to show more information about the combination
TPR
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 FPR
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 ACC
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 SPC
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 PPV
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 NPV
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 FDR
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 MCC
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Totals - 1 scale(s) combination0.730.270.730.730.070.990.930.166
Nucleic Acid Binding - mRNAinteractome, Castello et al., Cell 2011, 149:1393-1406+0.730.270.730.730.070.990.930.166
Totals - 2 scale(s) combination0.860.110.890.890.181.000.820.359
Nucleic Acid Binding - nonclassicalRBD, Castello et al., Cell 2011, 149:1393-1406+0.710.310.690.690.060.990.940.138
TOP-IDB, Dunker AK, Protein Pept Lett. 2008; 15(9): 956-963+0.710.310.690.690.060.990.940.137
Totals - 3 scale(s) combination0.970.040.960.960.391.000.610.606
Nucleic Acid Binding - nonclassicalRBD, Castello et al., Cell 2011, 149:1393-1406+0.710.310.690.690.060.990.940.138
Nucleic Acid Binding - interface_close+1, Terribilini et al., RNA 2006, 12:1450-1462+0.810.180.820.820.110.990.890.259
Knowledge-based membrane-propensity scale from 3D_Helix in MPtopo databases, Punta-Maritan, Proteins 2003, 50:114-121+0.680.400.600.600.050.990.950.092
Totals - 4 scale(s) combination0.990.030.970.970.491.000.510.688
Nucleic Acid Binding - nonclassicalRBD, Castello et al., Cell 2011, 149:1393-1406+0.710.310.690.690.060.990.940.138
Nucleic Acid Binding - interface_close+1, Terribilini et al., RNA 2006, 12:1450-1462+0.810.180.820.820.110.990.890.259
TOP-IDB, Dunker AK, Protein Pept Lett. 2008; 15(9): 956-963+0.710.310.690.690.060.990.940.137
Aggregation low - Tartaglia, J Mol Biol 2008, 380(2):425-36-0.650.500.510.500.030.980.970.048
Totals - 5 scale(s) combination0.990.010.990.990.701.000.300.824
Nucleic Acid Binding - nonclassicalRBD, Castello et al., Cell 2011, 149:1393-1406+0.710.310.690.690.060.990.940.138
Nucleic Acid Binding - interface, Nucleic Acids Res. 2011, 39:D277-D282+0.810.200.800.800.100.990.900.241
TOP-IDB, Dunker AK, Protein Pept Lett. 2008; 15(9): 956-963+0.710.310.690.690.060.990.940.137
Normalized relative frequency of coil, Isogai et al., Biopolymers 1980, 19:1183-1210+0.750.260.740.740.070.990.930.177
Aggregation low - Tartaglia, J Mol Biol 2008, 380(2):425-36-0.650.500.510.500.030.980.970.048

Score browser
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Protein ID Classification
(strength) 		Nucleic Acid Binding - nonclassicalRBD, Castello et al., Cell 2011, 149:1393-1406Nucleic Acid Binding - interface, Nucleic Acids Res. 2011, 39:D277-D282TOP-IDB, Dunker AK, Protein Pept Lett. 2008; 15(9): 956-963Normalized relative frequency of coil, Isogai et al., Biopolymers 1980, 19:1183-1210Aggregation low - Tartaglia, J Mol Biol 2008, 380(2):425-36
++++-reference sign
ENSP00000233468P (60%)0,00,10,20,30,4
ENSP00000170447N (55%)1,01,11,21,31,4
ENSP00000241502P (100%)2,02,12,22,32,4
ENSP00000247001P (65%)3,03,13,23,33,4
ENSP00000243563P/N (50%)4,04,14,24,34,4
ENSP00000274054N (80%)5,05,15,25,35,4
ENSP00000263257N (90%)6,06,16,26,36,4
ENSP00000257552N (55%)7,07,17,27,37,4
ENSP00000258742P (90%)8,08,18,28,38,4
ENSP00000296581N (65%)9,09,19,29,39,4
ENSP00000307181P (100%)10,010,110,210,310,4
ENSP00000292476N (70%)11,011,111,211,311,4
ENSP00000326261P (95%)12,012,112,212,312,4
ENSP00000320658N (95%)13,013,113,213,313,4
ENSP00000320309N (75%)14,014,114,214,314,4
ENSP00000293677N (55%)15,015,115,215,315,4
ENSP00000279068P (95%)16,016,116,216,316,4
ENSP00000319240N (95%)17,017,117,217,317,4
ENSP00000355599N (90%)18,018,118,218,318,4
ENSP00000365439P (90%)19,019,119,219,319,4
ENSP00000333001P (95%)20,020,120,220,320,4
ENSP00000345412P (80%)21,021,121,221,321,4
ENSP00000343054P (90%)22,022,122,222,322,4
ENSP00000365458P (90%)23,023,123,223,323,4
ENSP00000344401P (90%)24,024,124,224,324,4
ENSP00000363745P (100%)25,025,125,225,325,4
ENSP00000363573P (100%)26,026,126,226,326,4
ENSP00000348108P (90%)27,027,127,227,327,4
ENSP00000373080P (100%)28,028,128,228,328,4
ENSP00000360893P (75%)29,029,129,229,329,4
ENSP00000349428P (70%)30,030,130,230,330,4
ENSP00000361949P (80%)31,031,131,231,331,4
ENSP00000368563P (80%)32,032,132,232,332,4
ENSP00000355094N (75%)33,033,133,233,333,4
ENSP00000352612P (65%)34,034,134,234,334,4
ENSP00000327459N (100%)35,035,135,235,335,4
ENSP00000352438P (95%)36,036,136,236,336,4
ENSP00000329918P (55%)37,037,137,237,337,4
ENSP00000360867P (75%)38,038,138,238,338,4
ENSP00000365694P (100%)39,039,139,239,339,4
ENSP00000264073P (100%)40,040,140,240,340,4
ENSP00000360532P (85%)41,041,141,241,341,4
ENSP00000365444P (90%)42,042,142,242,342,4
ENSP00000360525N (95%)43,043,143,243,343,4
ENSP00000321997P (90%)44,044,144,244,344,4
ENSP00000347005P (100%)45,045,145,245,345,4
ENSP00000435839P (95%)46,046,146,246,346,4
ENSP00000413554P (100%)47,047,147,247,347,4
ENSP00000440433P (100%)48,048,148,248,348,4
ENSP00000448320P (95%)49,049,149,249,349,4
ENSP00000432845P (75%)50,050,150,250,350,4
ENSP00000442308P (90%)51,051,151,251,351,4
ENSP00000447605P (95%)52,052,152,252,352,4
ENSP00000414302P (100%)53,053,153,253,353,4
ENSP00000463058P (95%)54,054,154,254,354,4
ENSP00000449953P (95%)55,055,155,255,355,4
ENSP00000414921N (55%)56,056,156,256,356,4
ENSP00000461225P (100%)57,057,157,257,357,4
ENSP00000449740P (95%)58,058,158,258,358,4
ENSP00000406451P (80%)59,059,159,259,359,4
ENSP00000450024P (95%)60,060,160,260,360,4
ENSP00000427036N (65%)61,061,161,261,361,4
ENSP00000418721P (95%)62,062,162,262,362,4
ENSP00000389299P (100%)63,063,163,263,363,4
ENSP00000406754N (100%)64,064,164,264,364,4
ENSP00000438875N (75%)65,065,165,265,365,4
ENSP00000416060P (100%)66,066,166,266,366,4
ENSP00000462986P (65%)67,067,167,267,367,4
ENSP00000400142P (100%)68,068,168,268,368,4
ENSP00000446271P (100%)69,069,169,269,369,4
ENSP00000407310P (100%)70,070,170,270,370,4
ENSP00000447760P (95%)71,071,171,271,371,4
ENSP00000421592P (100%)72,072,172,272,372,4
ENSP00000422392N (65%)73,073,173,273,373,4
ENSP00000410769P (75%)74,074,174,274,374,4
ENSP00000407181P (100%)75,075,175,275,375,4
ENSP00000420929N (65%)76,076,176,276,376,4
ENSP00000420195P (100%)77,077,177,277,377,4
ENSP00000407724P (70%)78,078,178,278,378,4
NOTE: As a new feature, the input set has also been separated based on the individual assignment. You can download sequences closer to the positive set here and to the negative set here.
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