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ccSOL omics

ccSOL omics

The ccSOL algorithm predicts protein solubility using physico-chemical properties. ccSOL omics accepts multiple submissions and generates solubility profiles to allow the identification of soluble fragments within each polypeptide chain. The solubility profile represents a unique signature that is used to discriminate soluble and insoluble proteins obtained from heterologous expression experiments (accuracy of 78%). The server also computes single-point mutations throughout the whole protein sequence to identify susceptible areas.



 

Submission reference: 305328


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This module accepts a FASTA format file. There is another version available that allows submission via text.


Upload a set of proteins
(FASTA format, at least 1 and at most 104 sequences)

uploaded - top250bot250.fasta delete


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Sample data

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Escherichia coli proteins - 500 soluble and insoluble proteins from E. coli